Season 2 of Alphas should be starting any time now on SyFy; season 1 was okay.
I just started really getting into Weeds last year (it's in season 8 at the moment). I've heard it goes a little off the rails sometimes but it's addictive.
Nurse Jackie was great the first season, okay the 2nd, and great again the 3rd.
I don't know much about the original UK Shameless, but I lurv the US version.
I cry whenever Mad Men finishes a season. I need it like the air. AMC shows a marathon of older episodes every Sunday morning, I always watch them before going to bed lol.
Aaron Sorkin really got it right with The West Wing, but he's been striking out ever since. I haven't been getting into The Newsroom, it's too whitebread. But Sorkin deserved the Oscar for The Social Network -- I don't think anyone else in Hollywood could have made that story palatable. (Casting Jesse Eisenberg helped a lot too)