Let's see...MF cable show...
Wacky would be the host, sort of like Craig Ferguson on CBS. His monologues would consist of random thoughts about how he'll never get laid, that's he's "Not made like other people", and remarks about Natalie or Anna or Keira. When Natalie or Anna or Keira was on the show, he'd clam up and turn bright red, and we'd have five minutes of Keira asking, "Are you gonna ask me any questions, mate?". When Wacky got up it would be clear he soiled himself.
Gagh would pop up on your screen incessantly throughout the show and yell stream-of-consciousness drivel about so-and-so "stunning" J.R.R. Tolkien.
Mentalist would have his own Michael Jackson segment, where he would dress liek MJ and ask such pertinent questions as, "Wouldn't it be awesome if MJ had Veronica Mars to investigate all the allegations against him?"
BDM would be a semi-regular guest, all he would do is flirt with any female guest, staff member, audience member, or delivery woman, then whip out his penis for people to marvel at. All of this would be in a vain attempt to get Kristen Bell to notice him.
Eggs' segment would be exactly like every single episode of the Isaac Mizrahi Show.
So, who'd I leave out?