Acute (short-term) vs chronic (long-term) effects
Radiation sickness is generally associated with acute (a single large) exposure.[5][6] Nausea and vomiting are usually the main symptoms.[6] The amount of time between exposure to radiation and the onset of the initial symptoms may be an indicator of how much radiation was absorbed.[6] Symptoms appear sooner with higher doses of exposure.[7] The symptoms of radiation sickness become more serious (and the chance of survival decreases) as the dosage of radiation increases. A few symptom-free days may pass between the appearance of the initial symptoms and the onset of symptoms of more severe illness associated with higher doses of radiation.[6] Nausea and vomiting generally occur within 24-48 hours after exposure to mild (1-2 Gy) doses of radiation. Headache, fatigue, and weakness are also seen with mild exposure.[6] Moderate (2-3.5 Gy of radiation) exposure is associated with nausea and vomiting beginning within 12-24 hours after exposure.[6] In addition to the symptoms of mild exposure, fever, hair loss, infections, bloody vomit and stools, and poor wound healing are seen with moderate exposure.[6] Nausea and vomiting occur in less than 1 hour after exposure to severe (3.5-5.5 Gy) doses of radiation, followed by diarrhea and high fever in addition to the symptoms of lower levels of exposure.[6] Very severe (5.5-8 Gy of radiation) exposure is followed by the onset of nausea and vomiting in less than 30 minutes followed by the appearance of dizziness, disorientation, and low blood pressure in addition to the symptoms of lower levels of exposure.[6] Severe exposure is fatal about 50% of the time.[6]
Longer term exposure to radiation, at doses less than that which produces serious radiation sickness, can induce cancer as cell-cycle genes are mutated. If a cancer is radiation-induced, then the disease, the speed at which the condition advances, the prognosis, the degree of pain, and every other feature of the disease are not functions of the radiation dose to which the sufferer is exposed. In this case, function of dose is the probability chronic effects will develop.
Since tumors grow by abnormally rapid cell division, the ability of radiation to disturb cell division is also used to treat cancer (see radiotherapy), and low levels of ionizing radiation have been claimed to lower one's risk of cancer (see hormesis).