I've decided I want to do IT with Alistair, lol. He's disapproves sometimes, when I do things I need to do though. BUT he is easy to get back in good graces with if you sympathize with all his life stories. So far I have both Morrigan and Wynne with high approvals and some plot bonuses.
I tried to kill Flemeth yesterday, she is TOUGH. I almost had her, but I ran out of health poultices and lyrium potions with only a tiny bit of red left in her life bar and she wiped my party out. I think other people wait later in the game to do that quest, but I was so close I think I'll try again.